Research

Packages

Life of the unit

Next seminars

28 février 2019 Marianne Bourdon et Cédric Faquet état des lieux des différentes méthodes d’analyse qualitative

29 mars 2019 à définir à définir

Last publications

Updated

Bruno Giraudeau

Situation

Poste : PU-PH Biostatistique - Directeur-adjoint de l'unité SPHERE
Institution : Université de Tours
Email : bruno.giraudeau@univ-tours.fr

Publications scientifiques

Articles dans une revue internationale

• 1. Goldstein C, Giraudeau B, Weijer C, Taljaard M (2018) In reply: When and how should we cluster and cross over: methodological and ethical issues (letters 1 and 2). Can J Anaesth: doi: 10.1007/s12630-018-1239-3. [Epub ahead of print].
  
  
• 2. Taljaard M, Weijer C, Grimshaw J, Ali A, Brehaut J, Campbell M, Carroll K, Edwards S, Eldridge S, Forrest C, Giraudeau B, Goldstein C, Graham I, Hemming K, Hey S, Horn A, Jairath V, Klassen T, London A, Marlin S, Marshall JC, McIntyre L, McKenzie JE, Nicholls SG, Alison Paprica P, Zwarenstein M, Fergusson DA (2018) Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol. Trials, 19(1): 525. doi: 10.1186/s13063-018-2895-x.
  
  
• 3. Dibao-Dina C, Caille A, Giraudeau B (2018) Heterogeneous perception of the ethical legitimacy of unbalanced randomization by institutional review board members: a clinical vignette-based survey. Trials, 19(1): 440. doi: 10.1186/s13063-018-2822-1.
  
  
• 4. Cornillier H, Giraudeau B, Samimi M, Munck S, Hacard F, Jonville-Bera AP, Jegou M, d'Acremont G, Pham B, Chosidow O, Maruani A (2018) Effect of Diet in Chronic Spontaneous Urticaria: A Systematic Review. Acta Derm Venereol: doi: 10.2340/00015555-3015. [Epub ahead of print].
  
  
• 5. Goldstein C, Giraudeau B, Weijer C, Taljaard M (2018) When and how should we cluster and cross over: methodological and ethical issues. Can J Anaesth, 65(7): 760-5.
  
  
• 6. Maruani A, Boccara O, Bessis D, Guibaud L, Vabres P, Mazereeuw-Hautier J, Barbarot S, Chiaverini C, Blaise S, Droitcourt C, Mallet S, Marlin S, Lorette G, Woillard J, Jonville-Bera AP, Rollin J, Gruel Y, Herbreteau D, Goga D, Le Touze A, Leducq S, Gissot V, Morel B, Tavernier E, Giraudeau B, Groupe de Recherche de la Société Française de Dermatologie Pédiatrique (2018) Treatment of voluminous and complicated superficial slow-flow vascular malformations with sirolimus (PERFORMUS): protocol for a multicenter phase 2 trial with a randomized observational-phase design. Trials, 19(1): doi: 10.1186/s13063-018-2725-1.
  
  
• 7. Cornillier H, Giraudeau B, Munck S, Hacard F, Jonville-Bera AP, d'Acremont G, Pham B, Maruani A (2018) Chronic spontaneous urticaria in children - a systematic review on interventions and comorbidities. Pediatr Allergy Immunol, 29(3): 303-10.
  
  
• 8. Gillaizeau F, Senage T, Le Borgne F, Le Tourneau T, Roussel J, Leffondrè K, Porcher R, Giraudeau B, Dantan E, Foucher Y (2018) Inverse probability weighting to control confounding in an illness-death model for interval-censored data. Stat Med, 37(8): 1245-1258.
  
  
• 9. Diguisto C, Winer N, Descriaud C, Tavernier E, Weymuller V, Giraudeau B, Perrotin F (2018) Amnioinfusion for women with a singleton breech presentation and a previous failed external cephalic version: a randomized controlled trial. J Matern Fetal Neonatal Med, 31(8): 993-9.
  
  
• 10. Bodet-Contentin L, Frasca D, Tavernier E, Feuillet F, Foucher Y, Giraudeau B (2018) Ventilator-Free Day Outcomes Can Be Misleading. Crit Care Med, 46(3): 425-429.
  
  
• 11. Beslon V, Moreau P, Maruani A, Maisonneuve H, Giraudeau B, Fournier J (2018) Effects of Discontinuation of Urate-Lowering Therapy: A Systematic Review. J Gen Intern Med, 33(3): 358-66.
  
  
• 12. Reignier J, Boisramé-Helms j, Brisard L, Lascarrou J, Ait Hssain A, Anguel N, Argaud L, Asehnoune K, Asfar P, Bellec F, Botoc V, Bretagnol A, Bui H, Canet E, Da Silva D, Darmon M, Das V, Devaquet J, Djibre M, Ganster F, Garrouste-Orgeas M, Gaudry S, Gontier O, Guérin C, Guidet B, Guitton C, Herbrecht J, Lacherade J, Letocart P, Martino F, Maxime V, Mercier E, Mira JP, Nseir S, Piton G, Quenot JP Richecoeur J, Rigaud JP, Robert R, Rolin N, Schwebel C, Sirodot M, Tinturier F, Thévenin D, Giraudeau B, Le Gouge A, NUTRIREA-2 Trial Investigators & CRICS Group (2018) Enteral versus parenteral early nutrition in ventilated adults with shock: a randomised, controlled, multicentre, open-label, parallel-group study (NUTRIREA-2). Lancet, 391(127): 133-43.
  
  
• 13. Robert R, Le Gouge A, Kentish-Barnes N, Cottereau A, Giraudeau B, Adda M, Annane D, Audibert J, Barbier F, Bardou P, Bourcier S, Bourenne J, Boyer A, Brenas F, Das V, Desachy A, Devaquet J, Feissel M, Ganster F, Garrouste-Orgeas M, Grillet G, Guisset O, Hamidfar-Roy F, Hyacinthe AC, et al (2017) Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study). Intensive Care Med, 43(12): 1793-1807.
  
  
• 14. Robert R, Le Gouge A, Kentish-Barnes N, Cottereau A, Giraudeau B, Adda M, Annane D, Audibert J, Barbier F, Bardou P, Bourcier S, Bourenne J, Boyer A, Brenas F, Das V, Desachy A, Devaquet J, Feissel M, Ganster F, Garrouste-Orgeas M, et al (2017) Correction to: Terminal weaning or immediate extubation for withdrawing mechanical ventilation in critically ill patients (the ARREVE observational study). Intensive Care Me, 43(12): 1942-3.
  
  
• 15. Nicolas C, Le Gouge A, d'Alteroche L, Ayoub J, Georgescu M, Vidal V, Castaing D, Cercueil J, Chevallier P, Roumy J, Trillaud H, Boyer L, Le Pennec V, Perret C, Giraudeau B, Perarnau JM, Stic-Tips Group (2017) Evaluation of Doppler-ultrasonography in the diagnosis of transjugular intrahepatic portosystemic shunt dysfunction: A prospective study. World J Hepatol, 9(27): 1125-32.
  
  
• 16. Diguisto C, Le Gouge A, Giraudeau B, Perrotin F (2017) Mechanical cervicAl ripeninG for women with PrOlongedPregnancies (MAGPOP): protocol for a randomised controlled trial of a silicone double balloon catheter versus the Propess system for the slow release of dinoprostone for cervical ripening of prolonged p. BMJ Open, 7(9): e016069.
  
  
• 17. Taljaard M, Hemming K, Shah L, Giraudeau B, Grimshaw J, Weijer C (2017) Inadequacy of ethical conduct and reporting of stepped wedge cluster randomized trials: Results from a systematic review. Clin Trials, 14(4): 333-41.
  
  
• 18. Diguisto C, Piver E, Le Gouge A, Eboue F, Vaillant C, Maréchaud M, Goua V, Giraudeau B, Perrotin F (2017) First trimester uterine artery Doppler, sFlt-1 and PlGF to predict preeclampsia in a high-risk population. J Matern Fetal Neonatal Med, 30(13): 1514-9.
  
  
• 19. Gras-Le Guen C, Caille A, Launay E, Boscher C, Godon N, Savagner C, Descombes E, Gremmo-Feger G, Pladys P, Saillant D, Legrand A, Caillon J, Barbarot S, Rozé J, Giraudeau B (2017) Dry Care Versus Antiseptics for Umbilical Cord Care: A Cluster Randomized Trial. Pediatrics, 139(1): pii: e20161857.
  
  
• 20. Le Borgne F, Combescure C, Gillaizeau F, Giral M, Chapal M, Giraudeau B, Foucher Y (2017) Standardized and weighted time-dependent ROC curves to evaluate the intrinsic prognostic capacities of a marker by taking into account confounding factors. Statistical Methods in Medical Research: 962280217702416. doi: 10.1177/0962280217702416.
  
  
• 21. Caille A, Leyrat C, Giraudeau B (2016) A comparison of imputation strategies in cluster randomized trials with missing binary outcomes. Stat Methods Med Res, 25(6): 2650-69.
  
  
• 22. Machet L, Lanotte P, Giraudeau B, Leperlier M, Tavernier E, Maruani A (2016) Amber necklaces: reasons for use and awareness of risk associated with bacterial colonisation. Eur J Dermatol, 26(6): 580-5.
  
  
• 23. Agier MS, Boivin N, Maruani A, Giraudeau B, Gouraud A, Haramburu F, Jean-Pastor M, Machet L, Jonville-Bera AP (2016) Risk assessment of drug-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a disproportionality analysis using the French Pharmacovigilance Database. Br J Dermatol, 175(5): 1067-9.
  
  
• 24. Caille A, Kerry S, Tavernier E, Leyrat C, Eldridge S, Giraudeau B (2016) Timeline cluster: a graphical tool to identify risk of bias in cluster randomised trials. BMJ, 354: i4291.
  
  
• 25. Sautenet B, Bodet-Contentin L, Bigot A, Giraudeau B (2016) Strong heterogeneity of outcome reporting in systematic reviews. J Clin Epidemiol, 75: 93-9.
  
  
• 26. Tavernier E, Trinquart L, Giraudeau B (2016) Finding Alternatives to the Dogma of Power Based Sample Size Calculation: Is a Fixed Sample Size Prospective Meta-Experiment a Potential Alternative?. PloS One, 11(6): e0158604.
  
  
• 27. Nadal M, Giraudeau B, Tavernier E, Jonville-Bera AP, Lorette G, Maruani A (2016) Efficacy and Safety of Mammalian Target of Rapamycin Inhibitors in Vascular Anomalies: A Systematic Review. Acta Derm Venereol, 96(4): 448-52.
  
  
• 28. Ouldamer L, Bonastre J, Brunet-Houdard S, Body G, Giraudeau B, Caille A (2016) Dead space closure with quilting suture versus conventional closure with drainage for the prevention of seroma after mastectomy for breast cancer (QUISERMAS): protocol for a multicentre randomised controlled trial. BMJ Open, 6(4): e009903.
  
  
• 29. Le Borgne F, Giraudeau B, Querard AH, Giral M, Foucher Y (2016) Comparisons of the performance of different statistical tests for time-to-event analysis with confounding factors: practical illustrations in kidney transplantation. Stat Med, 35(7): 1103-16.
  
  
• 30. Porcher R, Leyrat C, Baron G, Giraudeau B, Boutron I (2016) Performance of principal scores to estimate the marginal compliers causal effect of an intervention. Stat Med, 35(5): 752-67.
  
  
• 31. Raffin D, Giraudeau B, Samimi M, Machet L, Pourrat X, Maruani A (2016) Corticosteroid Phobia Among Pharmacists Regarding Atopic Dermatitis in Children: A National French Survey. Acta Derm Venereol., 96(2): 177-80.
  
  
• 32. Bemer P, Léger J, Tandé D, Plouzeau C, Valentin A, Jolivet-Gougeon A, Lemarié C, Kempf M, Héry-Arnaud G, Bret L, Juvin M, Giraudeau B, Corvec S, Burucoa C, Gaborin L, GRIOGO Study Team (2016) How Many Samples and How Many Culture Media To Diagnose a Prosthetic Joint Infection: a Clinical and Microbiological Prospective Multicenter Study. J Clin Microbiol, 54(2): 385-91.
  
  
• 33. Giraudeau B, Higgins J, Tavernier E, Trinquart L (2016) Sample size calculation for meta-epidemiological studies. Stat Med, 35(2): 239-50.
  
  
• 34. Leyrat C, Caille A, Foucher Y, Giraudeau B (2016) Propensity score to detect baseline imbalance in cluster randomized trials: the role of the c-statistic. BMC Med Res Methodol, 16: 9.
  
  
• 35. Ouldamer L, Caille A, Giraudeau B, Body G (2015) Quilting Suture of Mastectomy Dead Space Compared with Conventional Closure with Drain. Ann Surg Oncol, 22(13): 4233-40.
  
  
• 36. Sautenet B, Caille A, Giraudeau B, Léger J, Vourc'h P, Buchler M, Halimi JM (2015) Deficits in information transfer between hospital-based and primary-care physicians, the case of kidney disease: a cross-sectional study. J Nephrol, 28(5): 563-70.
  
  
• 37. Barnes C, Boutron I, Giraudeau B, Porcher R, Altman D, Ravaud P (2015) Impact of an online writing aid tool for writing a randomized trial report: the COBWEB (Consort-based WEB tool) randomized controlled trial. BMC Med, 13(127): .
  
  
• 38. Dibao-Dina C, Caille A, Giraudeau B (2015) Unbalanced rather than balanced randomized controlled trials are more often positive in favor of the new treatment: an exposed and nonexposed study. J Clin Epidemiol, 68(8): 944-9.
  
  
• 39. Tavernier E, Giraudeau B (2015) Sample Size Calculation: Inaccurate A Priori Assumptions for Nuisance Parameters Can Greatly Affect the Power of a Randomized Controlled Trial. PLoS One, 10(7): e0132578.
  
  
• 40. Dibao-Dina C, Caille A, Sautenet B, Chazelle E, Giraudeau B (2014) Rationale for unequal randomization in clinical trials is rarely reported: a systematic review. J Clin Epidemiol, 67(10): 1070-5.
  
  

Articles dans une revue nationale

• 1. Maruani A, Giraudeau B, Abdo I, Raphaël P (2017) [Risk of ischaemic heart disease and cardiovascular mortality in patients with hidradenitis suppurativa]. Ann Dermatol Venereol, 144(3): 230-2.
  
  
• 2. Sautenet B, Halimi JM, Caille A, Giraudeau B (2015) [Outcomes in randomized trials: Typology, relevance and importance for their standardization. Example of renoprotection]. Presse Med, 44(11): 1096-102.
  
  
• 3. Dibao-Dina C, Caille A, Giraudeau B (2015) [Care and research: Are they ethically compatible?]. Presse Med, 44(11): 986-90.
  
  

Participations à des projets

• POPULAR : POPULation d’Analyse dans un essai randomisé en cluster : élaboration de Recommandations méthodologiques pour une estimation non biaisée de l'impact des interventions de type ‘organisation des soins’
  
  
• MEpiCluster : Etude Méta-Epidémiologique : essais en Cluster vs essais à randomisation individuelle
  
  

Encadrement/Accompagnement de thèses

• Murielle Mbekwe : Expression de l'effet clustering pour données binaire (2017-2020)
  
  
• Anaïs Le Jeannic : Evaluation de l’utilisation d’un outil de e/m-santé pour la prévention du suicide « StopBlues » promue par les villes : sur la diminution du nombre d’actes suicidaires, le recours à l’aide et les pratiques des médecins (2017-2020)
  
  
• Laetitia Bodet-Contentin : Critères de jugement dans les essais randomisés en soins intensifs : intérêt et limites des critères de type durée de ventilation mécanique & ventilator-free days (soutenue le 29 septembre 2017)
  
  
• Florent Le Borgne : Conception d’un outil simple permettant des analyses statistiques ajustées pour la valorisation des données de cohortes observationnelles de pathologies chroniques : application à la cohorte DIVAT. (soutenue le 30 septembre 2016)
  
  

Encadrement de stages

• Jeanne Simon-Pimmel : Performance d’un algorithme basé sur la procalcitonine en comparaison à un algorithme basé sur les recommandations ANAES pour le diagnostic d’infections néonatales: impact sur la prescription d’antibiotiques – Un essai randomisé en cluster en stepped-wedge (2017)
  
  
• Julie Akkoyun-Farinez : Age moyen des participants inclus dans un essai en cluster, par rapport à ceux inclus dans un essai à randomisation individuelle : étude méta-épidémiologique (2017)
  
  

Communications scientifiques

Poster dans un colloque international (idpers=1025)

• 1. Gillaizeau F., Le Borgne F., Rousseau C., Leyrat C., Giral M., Chapal M., Barbin L., Laplaud D., Giraudeau B., Foucher Y. The traditional multivariable logistic regression compared to propensity score: a study to put an end to preconceived ideas. 4th annual meeting of the UK Causal Inference Meeting, 13th-15th April 2016, London, 2016.
  
  

Communications orales dans un colloque national (idpers=1025)

• 1. Le Borgne F., Combescure C., Gillaizeau F., Giral M., Chapal M., Giraudeau B., Foucher Y. Courbes ROC standardisées dépendantes du temps pour évaluer les capacités pronostiques inhérentes à un marqueur en tenant compte des facteurs de confusion.. EPICLIN 2016 Strasbourg, 2016.
  
  
• 2. Gillaizeau F., Le Borgne F., Rousseau C., Leyrat C., Giral M., Chapal M., Barbin L., Laplaud D., Giraudeau B., Foucher Y. Régression logistique multivariée traditionnelle contre scores de propension : une étude pour mettre fin aux idées préconçues. 10e conférence francophone d'épidémiologie clinique (EPICLIN 2016) et 23e journées des statisticiens des centres de lutte contre le cancer, 25-27 mai 2016, Strasbourg, 2016.
  
  
• 3. Frasca D., Feuillet F., Bodet-Contentin L., Asehnoune K., Roquilly A., Mimoz O., Giraudeau B., Foucher Y. Le ventilator-free days comme critère de jugement dans les études de recherche clinique en réanimation : proposition d’une approche multi-état alternative. 10e Conférence Francophone d’Épidémiologie Clinique, Revue d'Épidémiologie et de Santé Publique, Volume 64, Supplement 3, May 2016, Pages S147, 2016.